Major Histocompatibility Complex class I (MHC-I) molecules bind and present peptides to cytotoxic T cells, protecting against pathogens and cancer.MHC-I is highly polymorphic and each allotype is promiscuous, and capable of binding a unique and diverse repertoire of peptide ligands.The peptide editing chaperone tapasin optimizes this allotype speci
Abstract Background Vitiligo is a disease that affects people of all skin shades and can impact their quality of life.Reliable evidence on the effectiveness and adverse events associated with the recent use of Janus kinase (JAK) inhibitors to treat vitiligo is needed.This protocol for a systematic review and meta-analysis seeks to collect evidence
A considerable difference between faux parlor palm experimental and theoretical results has been observed in the studies of segmented thermoelectric generators (STEGs).Because of simplicity, the approximate methods are widely used for design and optimization of the STEGs.This study is focused on employment of exact method for design and optimizatio
ABSTRACTFruit bodies (sporocarps) of wild mushrooms growing in natural environments play a substantial role in the preservation of microbial communities, for example, clinical and food-poisoning bacteria.However, the role of wild mushrooms as natural reservoirs of plant pathogenic bacteria remains almost entirely unknown.Furthermore, bacterial tran